我们报告了张力层造影差异相位对比度显微镜（T2DPC），这是一种用于同时测量相和各向异性的无定量标签层析成像方法。T2DPC扩展了差异相位对比显微镜（一种定量相成像技术），以突出光的矢量性质。该方法求解了从配备有LED矩阵，圆极偏振器和偏振敏感摄像机的标准显微镜获得的强度测量的各向异性样品的介电常数张量。我们证明了各种验证样品的折射率，双折射和方向的准确体积重建，并证明生物标本的重建极化结构是病理学的预测。

In this work, we explore a useful but often neglected methodology for robustness analysis of text generation evaluation metrics: stress tests with synthetic data. Basically, we design and synthesize a wide range of potential errors and check whether they result in a commensurate drop in the metric scores. We examine a range of recently proposed evaluation metrics based on pretrained language models, for the tasks of open-ended generation, translation, and summarization. Our experiments reveal interesting insensitivities, biases, or even loopholes in existing metrics. For example, we find that BERTScore ignores truncation errors in summarization, and MAUVE (built on top of GPT-2) is insensitive to errors at the beginning of generations. Further, we investigate the reasons behind these blind spots and suggest practical workarounds for a more reliable evaluation of text generation.

We study algorithms for detecting and including glass objects in an optimization-based Simultaneous Localization and Mapping (SLAM) algorithm in this work. When LiDAR data is the primary exteroceptive sensory input, glass objects are not correctly registered. This occurs as the incident light primarily passes through the glass objects or reflects away from the source, resulting in inaccurate range measurements for glass surfaces. Consequently, the localization and mapping performance is impacted, thereby rendering navigation in such environments unreliable. Optimization-based SLAM solutions, which are also referred to as Graph SLAM, are widely regarded as state of the art. In this paper, we utilize a simple and computationally inexpensive glass detection scheme for detecting glass objects and present the methodology to incorporate the identified objects into the occupancy grid maintained by such an algorithm (Google Cartographer). We develop both local (submap level) and global algorithms for achieving the objective mentioned above and compare the maps produced by our method with those produced by an existing algorithm that utilizes particle filter based SLAM.

Most camera lens systems are designed in isolation, separately from downstream computer vision methods. Recently, joint optimization approaches that design lenses alongside other components of the image acquisition and processing pipeline -- notably, downstream neural networks -- have achieved improved imaging quality or better performance on vision tasks. However, these existing methods optimize only a subset of lens parameters and cannot optimize glass materials given their categorical nature. In this work, we develop a differentiable spherical lens simulation model that accurately captures geometrical aberrations. We propose an optimization strategy to address the challenges of lens design -- notorious for non-convex loss function landscapes and many manufacturing constraints -- that are exacerbated in joint optimization tasks. Specifically, we introduce quantized continuous glass variables to facilitate the optimization and selection of glass materials in an end-to-end design context, and couple this with carefully designed constraints to support manufacturability. In automotive object detection, we show improved detection performance over existing designs even when simplifying designs to two- or three-element lenses, despite significantly degrading the image quality. Code and optical designs will be made publicly available.

We apply Physics Informed Neural Networks (PINNs) to the problem of wildfire fire-front modelling. The PINN is an approach that integrates a differential equation into the optimisation loss function of a neural network to guide the neural network to learn the physics of a problem. We apply the PINN to the level-set equation, which is a Hamilton-Jacobi partial differential equation that models a fire-front with the zero-level set. This results in a PINN that simulates a fire-front as it propagates through a spatio-temporal domain. We demonstrate the agility of the PINN to learn physical properties of a fire under extreme changes in external conditions (such as wind) and show that this approach encourages continuity of the PINN's solution across time. Furthermore, we demonstrate how data assimilation and uncertainty quantification can be incorporated into the PINN in the wildfire context. This is significant contribution to wildfire modelling as the level-set method -- which is a standard solver to the level-set equation -- does not naturally provide this capability.

The NASA Astrophysics Data System (ADS) is an essential tool for researchers that allows them to explore the astronomy and astrophysics scientific literature, but it has yet to exploit recent advances in natural language processing. At ADASS 2021, we introduced astroBERT, a machine learning language model tailored to the text used in astronomy papers in ADS. In this work we: - announce the first public release of the astroBERT language model; - show how astroBERT improves over existing public language models on astrophysics specific tasks; - and detail how ADS plans to harness the unique structure of scientific papers, the citation graph and citation context, to further improve astroBERT.

Graph neural networks (GNNs) have received great attention due to their success in various graph-related learning tasks. Several GNN frameworks have then been developed for fast and easy implementation of GNN models. Despite their popularity, they are not well documented, and their implementations and system performance have not been well understood. In particular, unlike the traditional GNNs that are trained based on the entire graph in a full-batch manner, recent GNNs have been developed with different graph sampling techniques for mini-batch training of GNNs on large graphs. While they improve the scalability, their training times still depend on the implementations in the frameworks as sampling and its associated operations can introduce non-negligible overhead and computational cost. In addition, it is unknown how much the frameworks are 'eco-friendly' from a green computing perspective. In this paper, we provide an in-depth study of two mainstream GNN frameworks along with three state-of-the-art GNNs to analyze their performance in terms of runtime and power/energy consumption. We conduct extensive benchmark experiments at several different levels and present detailed analysis results and observations, which could be helpful for further improvement and optimization.

临床试验是药物开发的重要一步，通常是昂贵且耗时的。在计算机试验中，是通过模拟和建模作为替代传统临床试验的临床试验进行数字进行的。在计算机试验中支持AI可以通过创建虚拟队列作为控件来增加案例组的规模。此外，它还可以实现试验设计的自动化和优化，并预测试验成功率。本文在三个主要主题下系统地回顾了论文：临床模拟，个性化预测建模和计算机辅助试验设计。我们专注于如何在这些应用中应用机器学习（ML）。特别是，我们介绍了机器学习问题的公式和每个任务的可用数据源。最后，我们讨论了现实世界中的Silico试验中AI的挑战和机遇。

对制造工艺的机器化的需求很大，因此单调劳动。一些需要特定技能的制造任务（焊接，绘画等）缺乏工人。机器人已在这些任务中使用，但是它们的灵活性受到限制，因为它们仍然很难通过非专家编程/重新编程，从而使它们无法访问大多数公司。机器人离线编程（OLP）是可靠的。但是，直接来自CAD/CAM的生成路径不包括代表人类技能的相关参数，例如机器人最终效应器的方向和速度。本文提出了一个直观的机器人编程系统，以捕捉人类制造技能并将其转变为机器人程序。使用连接到工作工具的磁跟踪系统记录人类熟练工人的演示。收集的数据包括工作路径的方向和速度。位置数据是从CAD/CAM中提取的，因为磁跟踪器捕获时的误差很明显。路径姿势在笛卡尔空间中转换，并在模拟环境中进行验证。生成机器人程序并将其转移到真正的机器人。关于玻璃粘合剂应用过程的实验证明了拟议框架捕获人类技能并将其转移到机器人方面的使用和有效性的直觉。

玻璃在我们的日常生活中非常普遍。现有的计算机视觉系统忽略了它，因此可能会产生严重的后果，例如，机器人可能会坠入玻璃墙。但是，感知玻璃的存在并不简单。关键的挑战是，任意物体/场景可以出现在玻璃后面。在本文中，我们提出了一个重要的问题，即从单个RGB图像中检测玻璃表面。为了解决这个问题，我们构建了第一个大规模玻璃检测数据集（GDD），并提出了一个名为GDNet-B的新颖玻璃检测网络，该网络通过新颖的大型场探索大型视野中的丰富上下文提示上下文特征集成（LCFI）模块并将高级和低级边界特征与边界特征增强（BFE）模块集成在一起。广泛的实验表明，我们的GDNET-B可以在GDD测试集内外的图像上达到满足玻璃检测结果。我们通过将其应用于其他视觉任务（包括镜像分割和显着对象检测）来进一步验证我们提出的GDNET-B的有效性和概括能力。最后，我们显示了玻璃检测的潜在应用，并讨论了可能的未来研究方向。